Regarded as an ethnohistorical treasure, the Popol Wuj narrative has been read exclusively as a freestanding, self-contained text used to inquire into a history far removed from when it was actually created. Consequently, the colonial context of the text itself has been minimized, including the central role of Dominican friar Francisco Ximénez as transcriber and translator of the only copy in existence. The present study delineates a historical trajectory of the Popol Wuj, reframing the narrative within its colonial ecclesiastic context. It explores the physical structure of Friar Ximénez’s 18th-century manuscript, preserved as MS 1515 by the Newberry Library in Chicago, to demonstrate that his work was first and foremost a series of religious treatises intended to carry out the conversion of the K’iche’ to Christianity. As a cautionary word, rather than revisiting the old, biased approach of questioning the authenticity and authorship of this Popol Wuj narrative, the current study suggests a broader reading, addressing the complexities intrinsic in this text, particularly the fact that the narrative was the result of the cultural contact between mendicant friars, whose main objective was to evangelize, and indigenous groups, who strived to maintain their cultural continuity by recording their oral history in the face of such a threat. Finally, this study invites scholars to ponder on the implications that the present structure of Ximénez’s manuscript (MS 1515) presents for future Popol Wuj studies as the narrative enters the age of electronic information and digital imaging.