This paper concerns the long-term evolution of labor in East Africa up to the twenty-first century. While it considers the classic themes of labor history, trade unions, strikes and politics, it is concerned with the broader question of how people relate to their environment, how their work is organized and what the economic consequences are. Taking 1500 as a bottom line, it proceeds to look at changes before and with the coming of imperialism and colonialism and the contradictions of colonial labor policy. It also considers how labor conditions have altered since independence. Mau Mau in Kenya and the institution of villagization in Tanzania, which both shed a light on labor conditions, receive particular attention. Since the majority of the population even in the twenty-first century are rural dwellers, there is much concern with agricultural and pastoral activities. If the greatest concentration is on Tanzania and Kenya, East Africa is defined broadly in part for purposes of comparison.