Over centuries, a variety of decentralized societies and centralized states have formed in territories across the western Sahel and southwest Sahara, and along the Niger and Senegal river valleys. Women have played central yet often unacknowledged roles in building these communities. By the late 11th century, some were rulers, as tombstones from the Gao region seem to suggest. A travelogue describing the Mali empire, and a chronicle from Songhay, tell stories of women who plotted political dissent or staged rebellions in the 14th–16th centuries. By and large, everyday women’s reproductive and productive labor sustained their families, and structured life in agricultural, pastoral, fishing, or trading communities. In the 1700s in Segu, women brewed mead, cultivated crops, dyed textiles, and participated in the building of fortifications. In Masina in the 1800s, girls attended qurʾanic school, and a woman was the custodian of the caliph’s library. Women also suffered great violence stemming from conflicts, forced displacement, and slavery. By the end of the 19th century, they made up a considerable portion (at times the majority) of enslaved individuals in the region. After the European conquest and creation of the French Soudan colony, the French administration imposed an export-oriented wage economy, in which women worked to supply crops and sustain infrastructure projects. From the regions of Kayes, Kita, and Nioro, many migrated to groundnut- or gold-producing regions of Senegambia. While women’s labor and migrations were seldom accounted for in administrative records, their attempts to leave unhappy marriages or escape enslavement do appear in court records. However, colonial domination was gendered: the administration ultimately shunned women’s emancipation efforts, seeking to channel its rule by reinforcing patriarchal authority in communities. In 1960, the Republic of Mali achieved independence. Under the democratic and military governments that followed, women built pan-African and transnational alliances. In 1991 and beyond, they fought to achieve more rights, and greater political power and representation. Their labor and migrations have continued to sustain a large portion of the economy. Post-2011, they have been both active participants in, and victims of, the conflicts that have engulfed the country, suffering displacement, loss of livelihood, and sexual violence, for which many have yet to receive justice.