From 1775 to 1815, empire served as the most pressing foreign relationship problem for the United States. Would the new nation successfully break free from the British Empire? What would an American empire look like? How would it be treated by other empires? And could Americans hold their own against European superpowers? These questions dominated the United States’ first few decades of existence and shaped its interactions with American Indian, Haitian, Spanish, British, and French peoples. The US government—first the Continental Congress, then the Confederation Congress, and finally the federal administration under the new Constitution—grappled with five key issues. First, they sought international recognition of their independence and negotiated trade deals during the Revolutionary War to support the war effort. Second, they obtained access to the Mississippi River and Port of New Orleans from Spain and France to facilitate trade and western settlement. Third, they grappled with ongoing conflict with Indian nations over white settlement on Indian lands and demands from white communities for border security. Fourth, they defined and protected American neutrality, negotiated a trade policy that required European recognition of American independence, and denied recognition to Haiti. Lastly, they fought a quasi-war with France and real war with Great Britain in 1812.