This article details the contributions of applied anthropology to public health, focusing on complementary and divergent interests, orientations, and methods. We emphasize areas where productive collaborations have occurred around convergent topics such as infectious and chronic disease, policy, interventions, and analysis of the social, political, and economic contexts that structure the conditions of health. Public health’s emphasis on community and advocacy provides a natural entry point for anthropology’s ethnographic method that emphasizes spending time with a community and understanding aspects of culture and health from its peoples’ perspectives. When a multidisciplinary team meets on a common interest, such as improving public health, everyone’s interests become better served if each discipline’s perspectives and values are recognized. Anthropologists with careers in public health can expect to engage in formative research to help develop the most appropriate health interventions, evaluate community uptake or rejection of public health initiatives, or critically examine the effects of national or global policies on local populations.