Clazomenae (mod. Klazumen), one of the twelve cities of the Panionium, situated on the south shore of the gulf of Smyrna on a small island joined to the mainland by a causeway. The original settlement was on the mainland, where large numbers of the terracotta sarcophagi peculiar to Clazomenae have been found. The move to the island came ‘from fear of the Persians’ (Paus. 7. 3. 9), apparently at the time of the Ionian Revolt (500–494 bce). About 600 bce Clazomenae successfully repulsed an attack by the Lydians under Alyattes, but later fell to Croesus. In the Delian League the city was at first assessed at one and a half talents, but during the Peloponnesian War this was raised to six and even to fifteen talents; the reason for this is uncertain. By the King's Peace (386 bce) Clazomenae came under Persian rule, which ended with Alexander (3) the Great. Clazomenae continued to function as a polis through the Hellenistic and imperial periods. Distinguished Clazomenian philosophers were Anaxagoras and Scopelianus.
Little remains of the ancient monuments, apart from public and private inscriptions, except for part of the original wall of the island site and remains of the harbour.