The notion of “self” is a non-technical one, bridging the areas of psychology and ethics or social relations. Criteria for selfhood include psychological unity or cohesion, agency, responsibility, self-consciousness, reflexivity, and capacity for relationships with others. “Self” is a modern concept with no obvious lexical equivalent in Greek (or Latin); the question therefore arises of the relationship between the modern concept and ancient thinking, as embodied in Greek literature. Three approaches to this question can be identified. One focuses on the idea that there is development within Greek literature towards an understanding of the self or person as a cohesive unit and bearer of agency and responsibility. Another approach sees certain aspects of Greek literature and philosophy as prefiguring some features of the modern concept of self. A third approach underlines the difference between the Greek and modern thought worlds in the formulation of concepts in this area, while also suggesting that Greek ideas and modes of presenting people can be illuminating to moderns, in part because of the challenge posed by their difference. These approaches draw on a range of evidence, including psychological vocabulary, characterization in Greek literature, and Greek philosophical analyses of ethical psychology. There are grounds for maintaining the credibility of all three approaches, and also valid criticisms that can be made of each of them.