Climate change was conceived as a “risk multiplier” that could exacerbate security risks and conflicts in fragile regions and hotspots where poverty, violence, injustice, and social insecurity are prevalent. The linkages have been most extensively studied for the African continent, which is affected by both climate change and violent conflict. Together with other drivers, climate change can undermine human security and livelihoods of vulnerable communities in Africa through different pathways. These include variability in temperature and precipitation; weather extremes and natural disasters, such as floods and droughts; resource problems through water scarcity, land degradation, and food insecurity; forced migration and farmer–herder conflict; and infrastructure for transport, water, and energy supply. Through these channels, climate change may contribute to humanitarian crises and conflict, subject to local conditions for the different regions of Africa. While a number of statistical studies find no significant link between reduced precipitation and violent conflict in Africa, several studies do detect such a link, mostly in interaction with other issues. The effects of climate change on resource conflicts are often indirect, complex, and linked to political, economic, and social conflict factors, including social inequalities, low economic development, and ineffective institutions. Regions dependent on rainfed agriculture are more sensitive to civil conflict following droughts. Rising food prices can contribute to food insecurity and violence. Water scarcity and competition in river basins are partly associated with low-level conflicts, depending on socioeconomic variables and management practices. Another conflict factor in sub-Saharan Africa are shifting migration routes of herders who need grazing land to avoid livestock losses, while farmers depend on land for growing their harvest. Empirical findings reach no consensus on how climate vulnerability and violence interact with environmental migration, which also could be seen as an adaptation measure strengthening community resilience. Countries with a low human development index (HDI) are particularly vulnerable to the double exposure to natural disasters and armed conflict. Road and water infrastructures influence the social and political consequences of climate stress. The high vulnerabilities and low adaptive capacities of many African countries may increase the probability of violent conflicts related to climate change impacts.