Among the socioenvironmental problems that have been determinant in the causes of climate change, deforestation represents one of the main ones. The environmental harms caused by deforestation include the extinction of flora and fauna species, the loss of soil fertility, and limits on regional sustainability, affecting efforts to mitigate climate change. The social harms include the reduction of communities’ capacities for development and the loss of ecosystem services such as water and soil fertility for subsistence, and phenomena such as illegal logging, when configured as organized crime, threaten the security of local communities. Despite government efforts to regulate this practice at local, regional, and global levels, it is still present in an illegal or uncontrolled manner in many countries. Deforestation is linked to soft law enforcement, the economic precariousness of the places where deforestation takes place (as a subsistence or illegal activity), and highly profitable illegal markets, therefore requiring a multifactorial response. Improving forest law enforcement and environmental conservation also requires strong political commitment across governments, as well as institutional, social (including native and Indigenous communities), economic, and environmental sector collaboration, promoting horizontal governance at all levels.