The re-entry experiences of women are an important area of inquiry given the continued rise in female imprisonment. Since most inmates will be released, reintegration is a chief policy concern. Like men, re-entering women tend to be disproportionately of color, poor, undereducated, and parents of minor children. What sets women apart from men, however, is the accumulation and frequency of the adversities they encounter. To be sure, co-occurring histories of trauma, mental health, and substance abuse—commonly referred to as the “triple threat”—along with physical health concerns and poverty, distinctly shape female re-entry. Women with children face additional burdens due to their status as mothers. In particular, women’s responsibilities for children before incarceration, contact with children during confinement, and expected parental roles after release are quite different than those of fathers. Pressures to assume mothering roles and challenges with parent-child reunification can further complicate re-entry. Women require social support to successfully transition from prison to home. Social support helps women meet competing demands related to housing, employment, transportation, childcare, and community supervision. This assistance typically comes from informal networks that are invaluable to re-entry success. At the same time, women’s relationships are often highly complicated and can be sources of stress. While prosocial relationships are protective, unhealthy ties can contribute to re-entry failure. With respect to formal social support, gender-responsive interventions that target the unique stressors of formerly incarcerated women offer the most promise for effecting post-release change. Yet, such programs are not widely available or accessible to this population. Finally, it is important to take stock of primary sources used in the study of female re-entry to identify ways to advance research and policy in this area.