Just as the factory assembly line replaced the farmer’s plow as the symbol of economic productivity at the beginning of the 19th century, so the computer and its software have replaced the assembly line at the beginning of the 21st century. In the United States, and in countries around the world, STEM (Science, Technology, Engineering and Mathematics) education has moved front and center in national discussions of both productivity and social justice. This article will include (a) a review of how the world of work has changed, with a special focus on the history and impact of digital technology since ca. 1970; (b) lessons from research about K-12 education—elementary, middle school, and secondary education—and about higher education; and (c) research about how to increase access to education, and facilitate achievement, for those who traditionally have been under-represented in STEM education. Rigorous research has demonstrated how psychological and sociological factors (e.g., self-concepts, instructor expectations, and social support) often make the difference between student success and failure. To fully contextualize consideration of STEM education, many advocate broadening STEM to STEAM by including the arts, or the arts and humanities, in building educational programs. In today’s world a young person who wishes to secure a better life for himself or herself would be well advised to study STEM. Furthermore, a nation that wishes to advance economically, while reducing the gap between the have’s and the have-not’s, should strengthen its STEM education infrastructure.