Africa has made significant progress at home and on the world stage that belies its image as the backwater of the global system. Far from being marginalized, African states have exercised their agency in the international system through an extensive mechanism of institutionalized diplomacy—anchored on the African Union (AU)—that they have forged over several decades of collective action. Changes are taking place in 21st-century Africa as a result of these collective efforts. Socioeconomic data from the African Development Bank, the United Nations Economic Commission for Africa, the United Nations, and the World Bank, indicate the economic, political, and demographic forces that are remaking Africa. Finally, the changes in Africa have implications for the evolving world order. Objective conditions warrant a reimagining of Africa as an agent in the international system, rather than as a passive victim of a predatory, anarchical order. Current challenges facing the post-war liberal international order make such reimagination imperative.