Albanian has been documented in historical texts only since the 16th century. In contrast, it had been in continuous contact with languages of the Latin phylum since the first encounters of Romans and Proto-Albanians in the 2nd century bce. Given the late documentation of Albanian, the different layers of matter borrowings from Latin and its daughter languages are relevant for the reconstruction of Proto-Albanian phonology and its development through the centuries. Latinisms also play a role in the discussion about the original home of the Albanians. From the very beginning, Latin influence seems to have been all-embracing with respect to the lexical domain, including word formation and lexical calquing. This is true not only for Latin itself but also for later Romance, especially for Italian historical varieties, less so for now extinct Balkan-Romance vernaculars like Dalmatian, and doubtful for Romanian, whose similarities with Albanian had been strongly overestimated in the past. Many Latin-based words in Albanian have the character of indirect Latinisms, as they go back to originally Latin borrowings via Ancient (and Medieval) Greek, and there is also the problem of learned borrowings from Medieval Latin. As for other Romance languages, only French has to be considered as the source of fairly recent borrowings, often hardly distinguishable from Italian ones, due to analogical integration processes. In spite of 19th-century claims in this respect, Latin (and Romance) grammatical influence on Albanian is (next to) zero. In Italo-Albanian varieties that have developed all over southern Italy since the late Middle Ages, based on a succession of immigration waves, Italian influence has been especially strong, not only with respect to the lexical domain but by interfering in some parts of grammar, too.