The term Afro Latina/os references people in Latin America and in the Latino United States who claim African ancestry. Although the use of the prefix Afrocan be traced back to the work of intellectuals in Cuba, Mexico, and Brazil at the beginning of the 20th century, usages were connected with anti-racist and African Diaspora struggles, organizing, and advocacy in the second half of the 20th century. More recently, the appellation Afro Latina/o has become mobilized in US Latina/o communities as a critique of the processes through which racial diversity and black populations in these communities have been rendered invisible. Because it conjures various meanings and foci, several authors engaged in the study of afrolatinidades suggest that hemispheric, transnational, and comparative approaches are necessary to appreciate the nuances of use, categorization, and experience as Afro Latina/os navigate complex histories and politics of race, ethnicity, and belonging in the United States and the Americas. The author argues that the term appellation does not resolve the complexities of racial subordination, racism, and self-making among Latin Americans and US Latina/os. He further suggests that sites of unintelligibility, confusion, and perplexity are valuable in thinking of “Afro-Latina/o” as a term that points to a cluster of urgent intellectual and political problems stemming from the irreducibility of individual experience to any term or concept. The increase in claims of Afro-Latina/o as a marker of identity must be calibrated by a consideration of how institutional sites and think tanks collaborate in the making and sedimentation of existing and emerging grids of legibility. At the same time, claiming Afro-Latina/o needs to be understood as a project related to yet distinct from one’s racial identification and relationship with blackness, and the experience of US Latina/os and other ethnic/racial minorities suggests that the work continues to be not only to understand how individuals and groups categorize themselves and others, but also to better grasp what it is that terms such as Afro-Latino/a do.