Latinx literature in the Midwest encompasses work created by authors from a variety of backgrounds, with authors of Mexican, Puerto Rican, and Cuban descent predominating in literature that takes locations throughout the region as its settings. Although much work focuses on Chicago, the multiple Latinidades of the region appear in fiction and poetry from across the region. Regarding genre, most of this literature falls into the categories of novel, short story, and poetry; however, works such as prose poems, novels in verse, heavily footnoted fiction, or metaliterary texts challenge genre boundaries and reveal Latinx literary innovation. This literature emerges from the history and experience of Latinx migration to the region, which dates back to the beginning of the 20th century, and, not surprisingly, that history often figures in the literature. Spanish-language Latinx literature about the Midwest also exists, and like its English-language counterpart, often addresses transnational experiences. Major publishers have made the work of Latinx authors in the Midwest well-known, yet there are also vibrant cultures of small press, community, and collective publishing, and self-publishing, through which Latinx authors have shared their talents with wider audiences in and beyond the region. Some of the themes addressed by Latinx literature in the Midwest are migration, with characters coming both from other regions of the United States and directly from Latin America; labor, mostly industrial and agricultural work, but also involving characters in the service sector and professionals; belonging and the question of what and where home is and how to create this space in the Midwest; environment and gentrification; transnationalism, often evoking different ethnic backgrounds from the present; family relationships; gender and sexuality, focusing on what it means to be Latinx and part of the LGBTQ community and situations of discrimination with families and workplaces; race, including Afro-Latinx characters; and religion and spirituality, looking not only to Catholicism, but also to Judaism and African diaspora–inspired systems of Orisha worship.