There is no single understanding of race to which everyone subscribes; it is a protean concept, accommodating various notions of human difference at the historical moments in which they emerge. Literary texts therefore do not represent a singular racial epistemology shared among Renaissance authors, readers, and audiences; rather, they demonstrate conflicting views about race, how it is determined, and what it tells us about individuals and groups of people. Scholars of Renaissance literature have explored what concepts of race do in specific cultural contexts, and the various ways racial differences were represented and understood before the advent of racial science in the late 17th century. Renaissance usages of the words race, raza, razza, and their linguistic equivalents denote, in their most benign sense, genealogy and lineage. Usages of these terms, nevertheless, locate individuals within genealogical and biological networks and insist that such networks are important to social organization. Race works as a tool for social organization that justifies varied types of domination, and in the Renaissance it drew from and informed established discourses of power—primarily religion, gender, and class. The concept bares vestiges of the word’s original definitions, asserting that certain aspects of identity are inheritable and inalterable, and then uses those aspects of identity to naturalize social hierarchies—White over Black, Christian over non-Christian, European over non-European. Race thus is a concept that intersects with cultural, somatic, sexual, and religious difference, and the Renaissance may be understood as a moment when race competes for dominance as a system of classification, justifying the rights of individuals and groups to rule over, disenfranchise, violate, and enslave others.