Figure 1. Functional neuroanatomical model for the fundamental thermoregulation pathways. Consult the text for description. Abbreviations: dorsal root ganglia (DRG), dorsal horn (DH) of the spinal cord, lateral parabrachial nucleus (LPB), preoptic area (POA) of the hypothalamus, dorsomedial hypothalamus (DMH), rostral raphe pallidus (rRPa), median preoptic area (MnPO), warm-sensitive (W-S) neurons, medial preoptic area (MPA), brown adipose tissue (BAT), prostaglandin E2 (PGE2), cutaneous vasoconstriction (CVC), sympathetic preganglionic neurons (SPNs), intermediolateral nucleus (IML), and ventral horn (VH) of the spinal cord.

Used with permission from Morrison (2016).