Ethics, corruption, and integrity do matter for society and are relevant topics to take into account in the research (and practice) of public administration and governance. The many views, perspectives, and interpretations that are available with respect to these issues can be integrated in a challenging framework. This framework takes the concept of integrity of governance as a starting point, with a focus on relevant moral values and norms for political and administrative behavior and a discussion of various forms of integrity violations in the public sector. Based on a large amount of research on “what helps to protect integrity and prevent integrity violations,” it specially pays attention to integrity management and integrity systems. The framework concerning ethics, corruption, and integrity of governance offers starting points for formulating an agenda for the future. This agenda should express the desirability of both an “integrity turn” in public administration and political science and an “empirical turn” in integrity research.