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Healthy and Pathological Neurocognitive Aging: Spectral and Functional Connectivity Analyses Using Magnetoencephalography
Gianluca Susi, Jaisalmer de Frutos-Lucas, Guiomar Niso, Su Miao Ye-Chen, Luis Antón Toro, Brenda Nadia Chino Vilca, and Fernando Maestú
Oscillatory activity present in brain signals reflects the underlying time-varying electrical discharges within and between ensembles of neurons. Among the variety of non-invasive techniques available for measuring of the brain’s oscillatory activity, magnetoencephalography (MEG) presents a remarkable combination of spatial and temporal resolution, and can be used in resting-state or task-based studies, depending on the goals of the experiment.
Two important kinds of analysis can be carried out with the MEG signal: spectral a. and functional connectivity (FC) a. While the former provides information on the distribution of the frequency content within distinct brain areas, FC tells us about the dependence or interaction between the signals stemming from two (or among many) different brain areas.
The large frequency range combined with the good resolution offered by MEG makes MEG-based spectral and FC analyses able to highlight distinct patterns of neurophysiological alterations during the aging process in both healthy and pathological conditions. Since disruption in spectral content and functional interactions between brain areas could be accounted for by early neuropathological changes, MEG could represent a useful tool to unveil neurobiological mechanisms related to the cognitive decline observed during aging, particularly suitable for the detection of functional alterations, and then for the discovery of potential biomarkers in case of pathology.
The aging process is characterized by alterations in the spectral content across the brain. At the network level, FC studies reveal that older adults experience a series of changes that make them more vulnerable to cognitive interferences.
While special attention has been dedicated to the study of pathological conditions (in particular, mild cognitive impairment and Alzheimer’s disease), the lack of studies addressing the features of FC in healthy aging is noteworthy. This area of research calls for future attention because it is able to set the baseline from which to draw comparisons with different pathological conditions.
Organizational psychology represents an important theoretical and practical field of contemporary psychological science that studies mental and behavioral phenomena that take place in individuals and groups belonging to social organizations.
From a historical point of view, the roots of this specialty can be traced to the psychological approaches to the world of industry and work that began to appear in the beginning of the 20th century. The discovery of the relevance of individual differences in both mental and behavioral processes paved the way to the creation of a scientific and technical knowledge that could maximize an adaptation of humans at work that would benefit industrial activities, would increase worker satisfaction, and bring progress and peace to all of society.
Such specialized knowledge has evolved during the past century through a series of stages that permitted a growing theoretical complexity and more efficient technological interventions. This evolution of basic topics includes the study of the human operator; humankind’s capacities and abilities; the influence of social factors upon people in the workplace; and the structures of all sorts of organizations created to obtain desired and needed goals. The relevance of social powers influencing the world of labor have made possible the creation of a rigorous and complex body of scientific knowledge that continuously provides information, advice, and help to modern society in its economic, social, and political structures.
Jeffrey Bond and Tony Morris
Australian sport psychology was effectively “launched” in conjunction with the establishment of the Australian Institute of Sport (AIS) in 1981. Prior to this date, sport psychology sat within the realm of a small number of research academics in tertiary institutions and many more unqualified practitioners with backgrounds in sport, hypnotherapy, medicine, and marketing and sales. The commencement of the legitimacy of the profession in the early 1980s correlated with the co-location of the AIS Sport Psychology Department with other sports medicine and sports science disciplines. From this rather humble but significant beginning, Australian sport psychology quickly became integrated into the training and competition plans of the vast majority of Australian Olympic sports and the developing professional football, tennis, golf, and cricket codes.
The rapid growth of the AIS and its team of qualified and experienced sport psychology practitioners, combined with international competition exposure, international conference presentations, reciprocal visits to international sports institutes, and Olympic training centers culminated in the inclusion of sport psychology within the auspices of the Australian Psychological Society (APS) and the accreditation of undergraduate and postgraduate tertiary programs in Australian universities. Applied sport psychology services are now a regular inclusion in most, if not all, Australian sports programs. An increasing emphasis on athlete and coach mental health in conjunction with the performance enhancement capability associated with sport psychology support has firmly entrenched the profession within the Australian sporting milieu.
Stiliani "Ani" Chroni and Frank Abrahamsen
The evolution in sport, exercise, and performance psychology in Europe goes back to the 1800s and spread from the east (Germany and Russia) to the west of the continent (France). Modern European sport psychology theorizing started with Wilhelm Wundt, who studied reaction times and mental processes in 1879, and Philippe Tissié, who wrote about psychological changes during cycling in 1894. However, Pierre de Coubertin was the one to put forward the first definition and promotion of sport psychology as a field of science. From there on, and despite obstacles and delays due to two world wars in Europe, sport psychology accelerated and caught up with North America. Looking back to the history of our disciplines, while sport, exercise, and performance psychology evolved and developed as distinct disciplines in Europe, sport and exercise psychology research appear to be stronger than performance psychology. The research advancements in sport and exercise psychology led to the establishment of the European sport psychology organization (FEPSAC) in the 1960s, as researchers needed an umbrella establishment that would accept the cultural and linguistic borders within the continent. From there on, education programs developed throughout Europe, and a cross-continent program of study with the collaboration of 12 academic institutions and the support of the European Commission was launched in the late 1990s. Applied sport psychology was practiced in the Soviet Union aiming to enhance the performance of their teams in the 1952 Olympics. Unfortunately, in many countries across Europe, research and practice are not comprehensively integrated to enhance sports and sportspersons, and while applied practice has room to grow, it also has challenges to tackle.
Vincent J. Granito
The history of sport, exercise, and performance psychology in North America dates back to the late 1800s. However, these professionals typically conducted research in the area of motor learning and development, with little connection to other efforts and researchers. They struggled to forge an identity with the parent disciplines of psychology and physical education. By the 1930s, sport psychology was beginning to take shape in the form of topics that would become the foundation of the field. Professionals were also starting to provide services to athletes, such as Coleman Griffith with the Chicago Cubs in 1938. The field came into its own during the 1950s and 1960s as established research labs and educational opportunities became available to students who would go on to develop further opportunities during the 1970s and 1980s. The scholarly journals were launched, professional organizations were set up, and graduate programs were created. Exercise psychology became a subdivision of the field during the 1970s fitness craze, and performance psychology developed into a specialty in the 1980s. This rich history provides a framework for the current makeup of the field and direction for the future.
Clinton Gahwiler, Lee Hill, and Valérie Grand’Maison
Since the 1970s, significant growth globally has occurred in the related fields of sport, exercise, and performance psychology. In Southern Africa, however, this growth has occurred unevenly and, other than isolated pockets of interest, there has been little teaching, research, or practice.
South Africa is an exception, however, even during the years of apartheid. A number of international sport psychology pioneers in fact visited South Africa during the 1970s on sponsored trips. Virtually all this activity took place in the economically advantaged sectors of the country, and it is only since the end of apartheid in 1994 that applied services have been extended to the economically disadvantaged areas through both government and private funding.
The 2010s have also seen a growing awareness in other Southern African countries, which have begun sporadically using (mainly foreign-based) sport psychology consultants. Among these countries, Botswana is currently leading the way in developing locally based expertise.
Throughout the Southern African region, sport, exercise, and performance psychology remain organizationally underdeveloped and unregulated. Local researchers and practitioners in the field face unique challenges, including a multicultural environment and a lack of resources. In working to overcome these challenges, however, they have the potential to significantly add value to the global knowledge base of sport, exercise, and performance psychology.
Philip Sayegh, David J. Moore, and Pariya Fazeli Wheeler
Since the first cluster of people with HIV was identified in 1981, significant biomedical advances, most notably the development of antiretroviral therapy (ART), have led to considerably increased life expectancy as well as a reduction in the morbidity and mortality associated with HIV/AIDS. As a result, HIV/AIDS is no longer considered a terminal illness, but rather a chronic illness, and many persons living with HIV/AIDS are beginning to enter or have already reached later life. In fact, Americans ages 50 years and older comprise approximately half of all individuals with HIV/AIDS and represent the most rapidly growing subpopulation of persons living with HIV/AIDS in the United States.
Despite significant advances in HIV/AIDS treatment and prognosis, older adults living with HIV (OALH) face a number of unique challenges and circumstances that can lead to exacerbated symptoms and poorer outcomes, despite demonstrating generally better ART adherence than their younger counterparts. These detrimental outcomes are due to both chronological aging and cohort effects as well as social and behavioral factors and long-term ART use. For instance, neurocognitive deficits and neuropsychiatric symptoms, including depression, anxiety, apathy, and fatigue, are often observed among OALH, which can result in feelings of loneliness, social isolation, and reduced social support. Taken together, these factors can lead to elevated levels of problems with everyday functioning (e.g., activities of daily living) among OALH. In addition, sociocultural factors such as race/ethnicity, ageism, sexism, homophobia, transphobia, geographic region, socioeconomic status and financial well-being, systemic barriers and disparities, and cultural values and beliefs play an influential role in determining outcomes.
Notwithstanding the challenges associated with living with HIV/AIDS in later life, many persons living with HIV/AIDS are aging successfully. HIV/AIDS survivor and community mobilization efforts, as well as integrated care models, have resulted in some significant improvements in overall HIV/AIDS patient care. In addition, interventions aimed at improving successful aging outcomes among OALH are being developed in an attempt to effectively reduce the psychological and physical morbidity associated with HIV disease.
Athletes’ transition out of elite sport has drawn the attention of psychologists in view of the number of problems retired athletes face with which they are generally unprepared to cope. Research over the past decades has revealed that athletic retirement should not be viewed as a dead-end stop but rather as a process of transition. The quality of this transition is influenced not only by the pre- and post-retirement phases but also by the challenges retiring elite athletes have faced at different levels of their development. Using the holistic athletic career model, challenges faced by retiring athletes are described at the athletic, psychological, psychosocial, academic, vocational, financial, and legal levels of their development. Particular attention is paid to the influence of these multilevel challenges on retirees’ mental health. In conclusion, the roles of psychologists in preparing and supporting elite athletes during the transition out of their sport are considered.
Despite high rates of mental illnesses, older adults face multiple barriers in accessing mental health care. Primary care clinics, and home- and community-based senior-serving agencies are settings where older adults routinely receive medical care and social services. Therefore, integration of mental health care with existing service delivery systems can improve access to mental health services and reduce the unmet mental health needs of seniors. Evidence suggests that with innovative components mental health provided in collaboration with primary care providers with or without co-location within primary care clinics can improve depression and anxiety. Home-based models for depression care are also effective, but more research is needed in examining home-based approaches in late-life anxiety treatment. It is noteworthy that integrative models are particularly helpful in expanding the reach in underserved communities: elders from minority and low-income backgrounds and homebound seniors.
Christopher Groves and Craig A. Anderson
This chapter reviews the history of modern psychological inquiry into human aggression and the development of aggression theory over time. Definitions of aggression-related phenomena are provided along with taxonomies of aggression that are frequently considered by psychological scientists. Modern, domain specific theories of aggression are detailed with emphasis placed on integrative theories of aggression. Special focus is paid to the scientific benefits and recent discoveries that are attributable to the use of integrative theories of aggression. Success in domains that serve as exemplars of systematically examining all known aggressive processes are identified as leaders in the productive future of aggression research.
Rebecca K. Dickinson, Tristan J. Coulter, and Clifford J. Mallett
As a basic psychological framework, humanistic theory emphasizes a strong interest in human welfare, values, and dignity. It involves the study and understanding of the unique whole person and how people can reach a heightened sense of self through the process of self-actualization. The focus within humanism to encourage and foster people to be “all they can be” and develop a true sense of self links to a strengths-based approach in sports coaching and the defining principles of positive psychology. In the field of sport and performance psychology, positive psychology has been influential as a discipline concerned with the optimal functioning and human flourishing of performers. Since the 2000s, many sport and performance psychologists have embraced positive psychology as a theoretical basis for examining consistent and superior human performance. However, in the modern history of psychological science, positive psychology is not a new phenomenon; rather, it stems from humanism—the traditional “third wave” in psychology (after the dominance of psychoanalytic and behaviorist approaches).
Sport is recognized as a potentially influential context through which people at all levels and backgrounds can thrive. The tendency to focus on performance outcomes, however—winning and losing—often overshadows the potential of sport to achieve this aspirational goal. As evidence of this view, many high-performing athletes are commenting on their distressing experiences to reach the top and the “culture of fear” they have been exposed to as they pursue their own and others’ (e.g., institutional) ambitions (e.g., medaling at the Olympic Games). Humanism concerns itself with the quality of a person’s life, which includes, but also extends beyond such objective and classifying achievements. It is a person-centered approach to understanding the individual and his or her psychological, emotional, and behavioral reality. It seeks to help people define this reality more clearly in such a way that will help them feel good and perform at a high level. Humanism has been, therefore, an important school of thought for improving the lives and experiences of people who play sport as well as those who perform in various other contexts.
David E. Guest
Human resources (HR) management addresses those policies, practices, and activities concerned with the management of people in organizations. Although it is typically considered at multiple levels of analysis, it provides an important context for the application of work and organizational psychology. Core research questions address the determinants of HR strategy and practices adopted by organizations and how these are linked to outcomes including in particular organizational performance and employee wellbeing. Much research explores this linkage process including how far HR practices are able to ensure employee abilities, motivation, and opportunities to contribute; the distinctive role of human capital; how employees react to these practices; and the steps management can take to ensure their effective implementation. Most research confirms an association between the adoption of a greater number of what are typically termed “high performance” or “high involvement” HR practices and higher organizational performance and employee wellbeing. However, doubts remain about the causal direction of the association. Continuing research challenges include how best to measure HR practices, understanding more about contextual influences, and incorporating more fully the role of employee attitudes and behavior including employee attributions about the motives of management in their use of HR practices.
Psychoanalyst Erik Erikson was the first professional to describe and use the concept of ego identity in his writings on what constitutes healthy personality development for every individual over the course of the life span. Basic to Erikson’s view, as well as those of many later identity writers, is the understanding that identity enables one to move with purpose and direction in life, and with a sense of inner sameness and continuity over time and place. Erikson considered identity to be psychosocial in nature, formed by the intersection of individual biological and psychological capacities in combination with the opportunities and supports offered by one’s social context. Identity normally becomes a central issue of concern during adolescence, when decisions about future vocational, ideological, and relational issues need to be addressed; however, these key identity concerns often demand further reflection and revision during different phases of adult life as well. Identity, thus, is not something that one resolves once and for all at the end of adolescence, but rather identity may continue to evolve and change over the course of adult life too.
Following Erikson’s initial writings, subsequent theorists have laid different emphases on the role of the individual and the role of society in the identity formation process. One very popular elaboration of Erikson’s own writings on identity that retains a psychosocial focus is the identity status model of James Marcia. While Erikson had described one’s identity resolution as lying somewhere on a continuum between identity achievement and role confusion (and optimally located nearer the achievement end of the spectrum), Marcia defined four very different means by which one may approach identity-defining decisions: identity achievement (commitment following exploration), moratorium (exploration in process), foreclosure (commitment without exploration), and diffusion (no commitment with little or no exploration). These four approaches (or identity statuses) have, over many decades, been the focus of over 1,000 theoretical and research studies that have examined identity status antecedents, behavioral consequences, associated personality characteristics, patterns of interpersonal relations, and developmental forms of movement over time. A further field of study has focused on the implications for intervention that each identity status holds. Current research seeks both to refine the identity statuses and explore their dimensions further through narrative analysis.
Amy E. Richardson and Elizabeth Broadbent
Cognitions about illness have been identified as contributors to health-related behavior, psychological well-being, and overall health. Several different theories have been developed to explain how cognitions may exert their impact on health outcomes. This article includes three theories: the Health Belief Model (HBM), the Theory of Planned Behavior (TPB), and the Common Sense Model (CSM), with the primary focus on the CSM. The HBM posits that cognitions regarding susceptibility to a health threat, the severity of the threat, and the benefits and costs associated with behavior, will determine whether or not a behavior is performed. In the TPB, behavior is thought to be a consequence of intention to act, which is shaped by attitudes regarding a behavior, subjective norms, and perceived behavioral control. The Common Sense Model (CSM) proposes that individuals form cognitive representations of illness (known as illness perceptions) as well as emotional representations, which are key determinants of coping behaviors to manage the illness. Coping behaviors are theorized to have direct relationships with physical and psychological health outcomes. Cognitive representations encompass perceptions regarding the consequences posed by the illness, its timeline, personal ability to control the illness, whether the illness can be cured or controlled by treatment, and the identity of the illness (including its label and symptoms). Emotional representations reflect feelings such as fear, anger, and depression about the illness. The development of illness representations is influenced by a number of factors, including personal experience, the nature of physical symptoms, personality traits, and the social and cultural context. Illness cognitions can vary considerably between patients and health care professionals. There are a number of methods to assess illness-related cognitions, and increasing evidence that modifying negative or inaccurate cognitions can improve health outcomes.
Victoria M. Esses
Migration is the movement of people from one location to another, either within a country (internal migration between cities or regions) or between countries (international migration). Migration may be relatively voluntary (e.g., for employment opportunities) or involuntary (e.g., due to armed conflict, persecution, or natural disasters), and it may be temporary (e.g., migrant workers moving back and forth between source and receiving areas) or permanent (e.g., becoming a permanent resident in a new country). The term immigration refers specifically to international migration that is relatively permanent in nature. Immigrants are those individuals who have moved to a new country on a relatively permanent basis. Of importance, refugees are a particular type of immigrant, defined and protected by international law. They are individuals who have been formally recognized as having fled their country of residence because of a well-founded fear of persecution, armed conflict, violence, or war. Until they are recognized as such, these individuals are asylum seekers—individuals who have claimed refugee status and are waiting for that claim to be evaluated. Despite the relative permanence of immigration, advances in transportation and communication mean that immigrants are able to travel to, spend time in, and communicate on a regular basis with their country of origin. As a result, what has been termed transnationalism may result, with individuals holding strong ties with, and actively participating in, both the country of origin and the new receiving country.
Migration often results in two or more cultures coming into contact. This contact is especially likely for international migration where immigrants from one national group (the society of origin) come into contact with members of a different national group (the receiving society). Culture may include specific beliefs, attitudes, and customs, as well as values and behaviors. The term acculturation refers to the changes that may occur when individuals from different cultures come into contact, with possible changes in both immigrants and members of the receiving society. Psychological theory and research suggest that acculturation is bidimensional, with changes potentially taking place along two dimensions—one representing the maintenance or loss of the original culture and the other representing the adoption or rejection of the new culture. This bidimensionality is important because it suggests that acculturation is not linear from original culture to new culture, but instead that individuals may simultaneously participate in the new culture and maintain their original culture. The two cultures may be expressed at different times, in different contexts, or may merge to form cultural expressions that have aspects of both cultures. With voluntary and involuntary migration at historically high levels, understanding the drivers of migration and its consequences for migrants and those with whom they come into contact are essential for global cooperation and well-being.
Emma V. Ward and David R. Shanks
It is well documented that explicit (declarative, conscious) memory declines in normal aging. Studies have shown a progressive reduction in this form of memory with age, and healthy older adults (typically aged 65+ years) usually perform worse than younger adults (typically aged 18–30 years) on laboratory tests of explicit memory such as recall and recognition. In contrast, it is less clear whether implicit (procedural, unconscious) memory declines or remains stable in normal aging. Implicit memory is evident when previous experiences affect (e.g., facilitate) performance on tasks that do not require conscious recollection of those experiences. This can manifest in rehearsed motor skills, such as playing a musical instrument, but is typically indexed in the laboratory by the greater ease with which previously studied information is processed relative to non-studied information (e.g., repetition priming). While a vast amount of research has accumulated to suggest that implicit memory remains relatively stable over the adult lifespan, and is similar in samples of young and older adults, other studies have in contrast revealed that implicit memory is subject to age-related decline. Improving methods for determining whether implicit memory declines or remains stable with age is an important goal for future research, as the issue not only has significant implications for an aging society regarding interventions likely to ameliorate the effects of age-related explicit memory decline, but can also inform our theoretical understanding of human memory systems.
Stephanie J. Wilson, Alex Woody, and Janice K. Kiecolt-Glaser
Inflammatory markers provide invaluable tools for studying health and disease across the lifespan. Inflammation is central to the immune system’s response to infection and wounding; it also can increase in response to psychosocial stress. In addition, depression and physical symptoms such as pain and poor sleep can promote inflammation and, because these factors fuel each other, all contribute synergistically to rising inflammation. With increasing age, persistent exposure to pathogens and stress can induce a chronic proinflammatory state, a process known as inflamm-aging.
Inflammation’s relevance spans the life course, from childhood to adulthood to death. Infection-related inflammation and stress in childhood, and even maternal stress during pregnancy, may presage heightened inflammation and poor health in adulthood. In turn, chronically heightened inflammation in adulthood can foreshadow frailty, functional decline, and the onset of inflammatory diseases in older age.
The most commonly measured inflammatory markers include C-reactive protein (CRP) and proinflammatory cytokines interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α). These biomarkers are typically measured in serum or plasma through blood draw, which capture current circulating levels of inflammation. Dried blood spots offer a newer, sometimes less expensive collection method but can capture only a limited subset of markers. Due to its notable confounds, salivary sampling cannot be recommended.
Inflammatory markers can be added to a wide range of lifespan developmental designs. Incorporating even a single inflammatory assessment to an existing longitudinal study can allow researchers to examine how developmental profiles and inflammatory status are linked, but repeated assessments must be used to draw conclusions about the associations’ temporal order and developmental changes. Although the various inflammatory indices can fluctuate from day to day, ecological momentary assessment and longitudinal burst studies have not yet incorporated daily inflammation measurement; this represents a promising avenue for future research.
In conclusion, mounting evidence suggests that inflammation affects health and disease across the lifespan and can help to capture how stress “gets under the skin.” Incorporating inflammatory biomarkers into developmental studies stands to enhance our understanding of both inflammation and lifespan development.
DeMond M. Grant and Evan J. White
Cognitive control is the ability to direct attention and cognitive resources toward achieving one’s goals. However, research indicates that anxiety biases multiple cognitive processes, including cognitive control. This occurs in part because anxiety leads to excessive processing of threatening stimuli at the expense of ongoing activities. This enhanced processing of threat interferes with several cognitive processes, which includes how individuals view and respond to their environment. Specifically, research indicates that anxious individuals devote their attention toward threat when considering both early, automatic processes and later, sustained attention. In addition, anxiety has negative effects on working memory, which involves the ability to hold and manipulate information in one’s consciousness. Anxiety has been found to decrease the resources necessary for effective working memory performance, as well as increase the likelihood of negative information entering working memory. Finally, anxiety is characterized by focusing excessive attention on mistakes, and there is also a reduction in the cognitive control resources necessary to correct behavior. Enhancing our knowledge of how anxiety affects cognitive control has broad implications for understanding the development of anxiety disorders, as well as emerging treatments for these conditions.
This article aims to provide a narrative overview on injury prevention in sport and performance psychology. Research and applied interest in psychological injury prevention in sport and performance psychology has risen in popularity over the past few decades. To date, existing theoretical models, pure and applied research, and practice-based evidence has focused on conceptualizing and examining psychological injury occurrence and prevention through stress-injury mechanisms, and predominantly in sport injury settings. However, given the inherited similarities across the different performance domains however, it is the authors’ belief that existing injury prevention knowledge can be transferable beyond sport but should be done with caution. A range of cognitive-affective-behavioral strategies such as goal setting, imagery, relaxation strategies, self-talk, and social support have been found beneficial in reducing injuries, particularly when used systematically (a) prior to injury occurrence as part of performance enhancement program and/or as a specific injury prevention measure, (b) during injury rehabilitation, and (c) as part of a return-to-activity process to minimize the risk of secondary injuries and reinjuries. Existing theoretical and empirical evidence also indicates that using cognitive-affective-behavioral strategies for injury prevention are effective when used as part of a wider, multi-modal intervention. Equally, such interventions may also need to address possible behavioral modifications required in sleep, rest, and recovery. Considering the existing empirical and anecdotal evidence to date, this paper argues that injury prevention efforts in sport and performance psychology should be cyclical, biopsychosocial, and person-centered in nature. In short, injury prevention should be underpinned by recognition of the interplay between personal (both physical and psychological), environmental, and contextual characteristics, and how they affect the persons’ cognitive-affective-behavioral processes before, during, and after injury occurrence, at different phases of rehabilitation, and during the return to activity or retirement from activity process. Moreover, these holistic injury prevention efforts should be underpinned by a philosophy that injury prevention is inherently intertwined with performance enhancement, with the focus being on the individual and their overall well-being.
Deborah M. Capaldi, David C. R. Kerr, and Stacey S. Tiberio
Intergenerational studies are key to informing research, preventive intervention, and policy regarding family influences on healthy development and maladjustment. Continuities in family socialization and contextual risks across generations, as well as genetic factors, are associated with the development of psychopathology—including externalizing problems in children—and with intergenerational associations in the use of marijuana, alcohol, tobacco, and other drugs; these continuities are reflected in the low-to-moderate associations generally found in prospective studies. Until recent years, estimates of intergenerational continuities in problem behaviors and the processes explaining such associations (e.g., parenting behaviors) have been based largely on retrospective reports by adults about their own parents’ behaviors. Now there are some long-term prospective studies spanning as many as 30 years that can assess linkages between behaviors in one generation and the next. Whereas such studies have considerable design and implementation challenges, and are very expensive, it is of critical importance to examine the magnitude of associations of behaviors across generations. For example, a modest association across generations suggests either that genetic factors have a limited influence on that behavior or that they are subject to considerable moderation by environmental factors. These prospective studies relate to theoretical developments regarding intergenerational influences that are reviewed—for example, individual differences in genetic sensitivity to environmental influences. The theoretical approach employed in the Oregon Youth Study—Three Generation Study is a Dynamic Developmental Systems (DDS) model of continuous feedback across systems throughout development. A new hypothesis encompassed by DDS is developmental congruence of intergenerational associations in problem behaviors. As used in geometry, congruence refers to figures of a similar shape and size. This term has been adapted to refer to the expectation that ages of onset and patterns of growth in key behaviors will show similarity across generations. This is based on the theory that genetic and temperamental factors increase an individual’s risk when these factors are expressed at sensitive developmental periods. Thus, the timing of these manifestations (e.g., susceptibility to deviant peer influences) is expected to be similar across generations. Developmental similarity is also likely due to continuities in social-risk context and family mechanisms, such as parenting.