Males and females differ—but only moderately—in moral judgment and morally relevant social behavior such as caring for others and aggression. Females more frequently use care-related concerns in their moral judgment. Research has to some extent supported traditional stereotypes of males as more assertive or independent (agency) and females as more relational or affiliative (communion). Males are on average more aggressive than females even after relational aggression is taken into account. In the expression of empathy and prosocial behavior, situational context plays a larger role for males than females. Males’ gender tendencies have been characterized as instrumental (“report talk,” object oriented, etc.) and females’ as socially and emotionally expressive (“rapport talk,” people oriented, etc.). In social relationships, adolescent girls generally engage in more intimate self-disclosure and active listening, provide more emotional support to one another, and emphasize affiliation and collaboration. Both biological and social experiential or cultural factors are involved in the formation of these morally relevant gender differences. Although average gender-linked differences in emphasis remain evident, a blend of instrumental and expressive characteristics may contribute to optimal morality for both genders. Sandra Bem termed the mixture of expressive (traditionally feminine) and instrumental (traditionally masculine) attributes in gender style “androgyny.” Highly androgynous adolescents and adults of both genders evidence more mature moral judgment and more adequate mental health.