The link between risk perception and risk response is not straightforward. There are several individual, community, and national factors that determine how climate change risk is perceived and how much of the perception translates to response. The nexus between risk perception and risk response in the context of water resource management at the individual, household, community, and institutional level has been subject of a large body of theoretical and empirical studies from around the globe. At the individual level, vulnerability, exposure, and cognitive factors are important determinants of climate change risk perception and response. At the community level, risk perception is determined by culture, social pressure, and group identity. Responses to risk vary depending on the level of social cohesion and collective action. At the national level, public support is a key determinant of institutional response to climate change, particularly for democratic nations. The level of global cooperation and major polluting countries’ willingness to curb their fair share of greenhouse gas emissions also deeply influence policymakers’ decisions to respond to climate change risk.