At the heart of social work, human rights is a set of interdependent and indivisible guiding principles with implications for meta-macro (global), macro (whole population), mezzo (at risk), micro (clinical), meta-micro (everyday life), and research interventions to eradicate social malaise and promote well-being. Human rights can be best understood vis-à-vis the UN Human Rights Triptych. This consists of the Universal Declaration of Human Rights, increasingly referred to as customary international law; the guiding principles, declarations, and conventions following it, such as the Guiding Principles to Eradicate Extreme Poverty, Declaration on the Rights of Indigenous Peoples, the Convention on the Rights of the Child, the Convention the Elimination of Racial Discrimination, and the Convention on the Elimination of All Forms of Discrimination Against Women; and implementation mechanisms, such as the filing of country reports on compliance to conventions, the Universal Periodic Review, thematic and country reports by special rapporteurs, and world conferences. This powerful idea, which emerged from the ashes of World War II, emphasizes five crucial notions: human dignity; nondiscrimination; civil and political rights; economic, social, and cultural rights; and solidarity rights. The hope is that every person, everywhere, will have their human rights realized. Only chosen values endure. The challenge is the creation of a human rights culture, which is a lived awareness of these principles in one’s mind, spirit, and body, integrated into our everyday lives. Doing so will require vision, courage, hope, humility, and everlasting love, as the Indigenous spiritual leader Crazy Horse reminded us.